Henley JM ; Mynlieff M ; Lindstrom JM ; Oswald RE ;

Brain Res vol. 364 (2)   pp. 405-8, 5 Fev 1986

Polyclonal and monoclonal antibodies raised against acetylcholine receptors from Torpedo californica and Electrophorus electricus electroplaque were tested for interaction with the [125I]alpha- bungarotoxin binding protein of goldfish brain. A subset of monoclonal antibodies which recognize the main immunogenic region of the alpha subunit of the Electrophorus acetylcholine receptor interacted at high affinity with the [125I]alpha-bungarotoxin binding protein. Using immunofluorescence, these antibodies were shown to label the same layers of the optic tectum as [125I]alpha-bungarotoxin.

Animal ;  Antibodies,Monoclonal ;  Comparative Study ;  Cross Reactions ;  Electric Organ: immunology ;  Electrophorus ;  Epitopes: analysis ;  Goldfish ;  Receptors,Cholinergic: immunology ;  Superior Colliculus: immunology ;  Support,Non-U.S.Gov't ;  Support,U.S.Gov't,Non-P.H.S. ;  Support,U.S.Gov't,P.H.S. ;  Torpedo ;  52290 ;