Oldach D ; Brown E ; Rublee P ;

Md Med J vol. 47 (3)   pp. 113-9, Mai 1998

Institute of Human Virology, University of Maryland School of Medicine, North Carolina, Greensboro, NC, USA.

Toxin-producing estuarine dinoflagellates have been linked with the occurrence of fish kills and the development of a novel clinical illness syndrome among persons exposed to waters during fish kill events. The prototype organism of this group, Pfiesteria piscicida, has an extremely complex life cycle, making traditional methods used for environmental monitoring of harmful algal blooms less reliable. The response to fish kill events and the occurrence of human illness in Maryland in 1997 is reviewed, with particular emphasis on problems in organism detection. Current and anticipated classical and molecular methodologies for the detection of Pfiesteria and Pfiesteria-like organisms are reviewed. Development of these capabilities will be of critical importance in defining the epidemiology of human illness related to environmental exposure to Pfiesteria, and in developing public health strategies to predict and prevent such illness.

Animal ;  Dinoflagellida: pathogenicity ;  Environmental Exposure: adverse effects ;  Environmental monitoring ;  Fish Diseases: etiology ;  Fishes ;  Human ;  Marine Toxins: adverse effects: analysis ;  Risk factors ;  2410 ;